A brief review of complex regional pain syndrome and current management.
Annals of medicine December 1, 2024 Alaa Abd-Elsayed, Cain W Stark, Natasha Topoluk et al. 41 citations
Complex regional pain syndrome (CRPS) is a rare but debilitating chronic pain condition with a complex and poorly understood pathophysiology, making diagnosis and treatment challenging. Diagnosis is by exclusion, and the Budapest diagnostic criteria have helped standardize definitions, but the underlying pathways remain unclear. Two types exist: CRPS type 1 (no neuronal injury) and type 2 (with neuronal injury). Management ranges from non-invasive therapies like physical and psychological therapy to invasive options such as dorsal root ganglion stimulation and amputation. Multimodal treatment is ideal, but more research is needed to understand CRPS development and to conduct robust clinical trials for therapies.