Risks of using psilocybin in treatment of treatment-resistant depression
Journal of Education, Health and Sport March 7, 2025 Michał Orzechowski, Joanna Orzechowska, Paulina Fijałek et al.
As depression rates rise globally, psilocybin shows promise as a treatment for treatment-resistant depression, but its safe clinical use requires clear safety parameters. This paper reviews risks associated with psilocybin therapy, drawing on a literature search of PubMed and Google Scholar for studies on challenges and risks in treating treatment-resistant depression. It aims to help understand these risks as a basis for safety-focused treatment protocols.