Joanne Stubley

The Tavistock Trauma Service, The Tavistock and Portman NHS Foundation Trust, London, UK.

2 papers in the library · 1 citation · publishing 2025-2026

Papers

Clinical conceptualisation of PTSD in psilocybin treatment: disrupting a pre-determined and over-determined maladaptive interpretive framework

Therapeutic Advances in Psychopharmacology June 8, 2025 Nadav Liam Modlin, Victoria Williamson, Carolina Maggio et al. 1 citation

PTSD is a common and debilitating condition that current treatments only partially address. This review examines psilocybin, a classical psychedelic, as a potential therapeutic agent. It synthesizes recent literature on psychedelic therapies for trauma-related conditions, including treatment-resistant depression and end-of-life anxiety. The authors propose a conceptual framework viewing PTSD as a maladaptive interpretive framework that psilocybin may disrupt through its psychopharmacological properties and subjective effects. A clinical narrative illustrates this process. Recommendations emphasize rigorous, trauma-informed protocols for safe administration in medical research settings.

DOI: 10.1177/20451253251342319 Psilocybin Anxiety Psychotherapist Cognition +4

Psychodynamic Perspectives on Psychedelic States and Treatment Contexts: A Conceptual and Clinical Introduction.

Psychodynamic psychiatry June 1, 2026 Nadav Liam Modlin, Zsofia Elek, Carolina Maggio et al.

Psychedelic therapy may help people access unconscious mental content—preverbal, dissociated, or developmentally buried material—that emerges through bodily sensations, symbolic images, and intense emotions. A psychodynamic framework, drawing on psychoanalytic theory, can guide clinicians in working with this material across four phases: screening, preparation, the treatment session, and follow-up integration. Although neurobiological mechanisms like 5-HT2A receptor activation are well studied, unconscious processes remain underexplored. The authors argue that psychoanalytic models, though currently underrepresented, can deepen understanding of therapeutic change beyond symptom reduction and should inform future research, training, and individualized care as psychedelic treatments move toward broader clinical use.

DOI: 10.1521/pdps.2026.54.2.338 Full text MDMA-Assisted Therapy Classical psychedelics Psychedelic treatment Psychodynamic psychiatry +1