Sex and Age Differences in Ketamine Efficacy and Safety in Chronic Pain Alleviation.
Journal of clinical medicine June 16, 2025 Gisèle Pickering, Marion Voute, Marc Sorel et al. 2 citations
A one-year observational study of 585 chronic pain patients found no sex or age differences in how well ketamine relieved pain, anxiety, or depression. Women reported more adverse events than men (19% vs. 13%). Among 329 patients who received two or more doses, no sex or age differences appeared. A single ketamine dose may be more effective for men than women, particularly younger men.