Exploring psilocybin's role in mental health and palliative medicine: a path to improved well-being.
Expert opinion on emerging drugs June 1, 2025 Maria-Alejandra Umbacia, Marta Ximena Leon, Jose-Manuel Quintero et al.
Psilocybin, a psychedelic drug, is being studied for medicinal use, particularly in adult psychiatry and palliative care. Clinical trials show it may benefit patients with treatment-resistant depression and those in palliative care, often in specialist centers. It acts rapidly by targeting the 5HT2A receptor. Its psychoactive effects are well documented, but their clinical importance is debated. Many questions remain about its efficacy for other conditions and its role in psychotherapy.