Mania following use of ibogaine: A case series.
The American journal on addictions April 1, 2015 Cole J Marta, Wesley C Ryan, Alex Kopelowicz et al. 17 citations
Ibogaine, a naturally occurring hallucinogen used illegally for addiction treatment, can trigger manic episodes even in people with no prior bipolar diagnosis. This case series reports three patients who developed mania after using unregulated ibogaine—two for self-treating addictions and one for psycho-spiritual purposes. No previous reports of ibogaine-induced mania exist in the literature. Clinicians encountering new-onset mania should inquire about substance use, especially ibogaine, given its growing popularity among vulnerable populations seeking addiction treatment. The authors advise discussing the lack of safety and efficacy data with patients considering ibogaine.