Psilocybin for disorders of consciousness: A case-report study.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology May 1, 2025 Paolo Cardone, Pablo Núñez, Naji L N Alnagger et al. 7 citations
A patient in a minimally conscious state plus received psilocybin, a classic psychedelic, for the first time. No increase in overt behavioral repertoire was observed on validated scales, but new spontaneous behavior not previously seen emerged, and brain complexity, measured by the Lempel-Ziv complexity index, increased with changes in underlying periodic rhythms. This case report contributes to future investigations of psychedelics for disorders of consciousness and the link between brain complexity and consciousness.