Processing of self-related thoughts in experienced users of classic psychedelics: A source localisation EEG study.
Progress in neuro-psychopharmacology & biological psychiatry January 10, 2025 Anastasia Ruban, Mikołaj Magnuski, Justyna Hobot et al. 1 citation
People who use psychedelics in natural settings show weaker increases in alpha and beta brainwave power when thinking about themselves, compared to non-users, especially in regions like the posterior cingulate cortex that handle self-related information and memory. However, these differences were not replicated in a second, smaller dataset, limiting confidence in the finding. The results contribute to ongoing debate about how long psychedelic effects last in brain circuits linked to self-processing and question the specific role of default-mode network hubs in such changes.