Functional connectivity of the default mode network predicts subsequent polysomnographically measured sleep in people with symptoms of insomnia.
Neuroreport October 4, 2023 William D S Killgore, Samantha Jankowski, Kymberly Henderson-Arredondo et al. 19 citations
Among 20 young adults with insomnia symptoms, resting-state functional connectivity between the default mode network (DMN) and certain cortical regions before bedtime predicted objectively measured sleep quality. Greater connectivity between the DMN and cortical areas involved in executive function and complex cognition was associated with more total sleep time, more REM sleep, and higher sleep efficiency, while connectivity with the pons was linked to lower sleep efficiency. The findings suggest that pre-sleep DMN activation may contribute to insomnia by supporting ruminative thinking, and that interventions to suppress such activation could improve sleep.