Impact of psychedelics on craving in addiction: A systematic review.
Journal of psychopharmacology (Oxford, England) February 1, 2025 Sophie-Athéna Chapron, Guilhem Bonazzi, Laura Di Lodovico et al. 5 citations
A systematic review of 31 studies involving 2639 participants found that 12 studies reported a significant decrease in craving for alcohol, opioids, cocaine, or tobacco after psychedelic use. However, all but two studies had moderate to high risk of bias due to methodological issues, so the promising anti-craving effects must be interpreted cautiously. The review highlights the need for larger, well-controlled trials to better understand psychedelics' effects on craving, a core symptom of substance use disorders and a predictor of relapse.