Self-regulation training for people with knee osteoarthritis: a protocol for a feasibility randomised control trial (MiNT trial).
Frontiers in pain research (Lausanne, Switzerland) January 1, 2023 Ramakrishnan Mani, Divya Bharatkumar Adhia, Sharon Awatere et al. 3 citations
Knee osteoarthritis (OA) is a chronic pain condition linked to altered brain activity. Self-regulation training, such as mindfulness meditation (MM) and electroencephalography neurofeedback (EEG-NF), may reduce pain. This double-blind, three-arm randomized controlled feasibility trial will compare MM plus usual care, EEG-NF plus usual care, and usual care alone. Participants with knee OA will be recruited from the community and healthcare practices; interventions involve 20-minute sessions, four times weekly for three weeks. Feasibility measures include recruitment, adherence, retention, and safety. Secondary outcomes are assessed at baseline, immediately post-intervention, and at three months. Qualitative interviews will explore participants' experiences, barriers, facilitators, and acceptability, including Māori perspectives. Results will inform a full randomized controlled trial.