Sunil K Aggarwal

2 papers in the library · 5 citations · publishing 2023

Papers

Integrative Oncology's 30-Year Anniversary: What Have We Achieved? A North American Naturopathic Oncology Perspective.

Integrative cancer therapies January 1, 2023 Leanna J Standish, Sonia M Malani, Ksenia Lynch et al. 5 citations

Over the past 30 years, integrative oncology has made valuable advances: intravenous high-dose ascorbate has clinical applications with certain chemotherapies; whole-body, extracorporeal, and locoregional hyperthermia are used for solid tumors including brain tumors; PDL-1 testing and immunotherapies show excellent outcomes in a subgroup of cancer patients; tumor DNA sequencing, including circulating tumor DNA, enables personalized precision treatments; better understanding of glucose metabolism has led to therapies like intermittent fasting and metformin; medical cannabis helps with chemotherapy side effects and shows anti-proliferative promise; psychoneuroendocrinoimmunology has expanded understanding of tumorigenesis and holistic immune regulation; psychedelic-assisted psychotherapy is gaining traction for cancer-related existential distress; spiritual health is now measurable with an NIH-validated scale; and mind-body therapies effectively reduce cancer-related distress.

DOI: 10.1177/15347354231178911 Full text Cannabis Psychedelic therapy Circulating tumor dna Hyperthermia +3

Reductions in anxiety and depression symptoms in a subset of outpatients with problematic substance use who received ketamine-assisted psychotherapy: a two-year retrospective chart review.

Frontiers in psychiatry January 1, 2023 Emily Whinkin, Therry Rose J Eparwa, Michelle C Julseth et al.

In patients with problematic substance use, ketamine-assisted psychotherapy (KAP) was associated with significant reductions in anxiety and depression symptoms, as measured by the GAD-7 and PHQ-9 scales. The average GAD-7 score decreased by 6.71 points, and the average PHQ-9 score decreased by 7.44 points. Improvements in psychosocial and spiritual well-being, measured by the NIH-HEALS scale, increased by an average of 5.13 points but were not statistically significant. Compared to the broader KAP patient population, those with problematic substance use showed significantly greater reductions in anxiety and depression. Undergoing one to six KAP sessions may be a useful therapy for reducing these symptoms in this population.

DOI: 10.3389/fpsyt.2023.1160442 Full text Anxiety Depression Ketamine-assisted psychotherapy Psychometrics +2