Ketamine-assisted psychotherapy in adolescents with multiple psychiatric diagnoses.
Frontiers in psychiatry January 1, 2023 Philip E Wolfson, Julane Andries, Daniel Ahlers et al. 27 citations
Ketamine-assisted psychotherapy (KAP) shows promise for treating adolescent mental disorders, though research is early. Four adolescents aged 14–19 with treatment-resistant depression, bipolar disorder, eating disorders, anxiety, panic, and trauma-related symptoms received sublingual ketamine followed by intramuscular ketamine. Each had symptomatic and functional improvements, and the treatment was well-tolerated. Rapid resolution of symptoms often occurs within months but is not inevitable. Family involvement appears essential to success. This modality may expand psychiatric treatment options.