Exploring psilocybin-assisted psychotherapy in the treatment of methamphetamine use disorder
Frontiers in Psychiatry March 14, 2023 Jonathan Brett, Elizabeth Knock, Paul Liknaitzky et al. 16 citations
Methamphetamine use disorder is a chronic condition with high relapse rates and limited effective treatments. Contingency management and psychotherapy show modest efficacy, while pharmacological options have little to no benefit. Psilocybin-assisted psychotherapy is emerging as a promising approach for substance use disorders, though no studies have yet examined it for methamphetamine use disorder. This review presents the rationale for using psilocybin-assisted psychotherapy to treat methamphetamine use disorder and describes practical considerations from early experience designing and implementing four clinical trials on this approach.