EFFECTS OF PSYCHOTROPIC DRUGS UPON THE EYE MOVEMENTS WITH CLOSED EYES
Psychiatry and Clinical Neurosciences June 1, 1967 Y Shimazono, Katsumi Ando, Takashi Tanaka et al. 4 citations
In 45 normal subjects, horizontal eye movements changed after psychotropic drugs. Amobarbital and chlorpromazine gradually eliminated rapid eye movements. LSD-25 increased rapid movements in 80% of subjects and produced large, slow pendular movements in about half, especially among those showing euphoria, disinhibition, and ecstasy. Psilocybin caused similar pendular movements but with longer duration. Methamphetamine and epinephrine initially decreased slow movements and increased rapid ones; epinephrine later transiently increased slow movements. The findings suggest different drugs distinctly alter eye movement patterns, possibly reflecting their mechanisms of action.