Set and setting predict psychopathology, wellbeing and meaningfulness of psychedelic experiences: a correlational study.
Expert review of clinical pharmacology January 1, 2024 Lucas F Borkel, Jaime Rojas-Hernández, Luis Alberto Henríquez-Hernández et al. 40 citations
Growth motivations for using psychedelics, natural settings, and the presence of significant others during use predict less psychopathology, greater wellbeing, and more meaningful experiences. Problematic motivations predict greater psychopathology, lower wellbeing, and do not predict meaningfulness. These findings come from an online survey of 1022 Spanish-speaking participants, using a newly developed Psychedelic Use Scale to measure use of nine substances including LSD, psilocybin, and MDMA. The results suggest experimental hypotheses for future clinical trials and longitudinal studies.