Transcranial magnetic stimulation and intravenous ketamine combination therapy for treatment-resistant bipolar depression: A case report
Frontiers in Psychiatry September 21, 2022 Laurent Elkrief, Olivier Payette, Jean-Nicolas Foucault et al. 15 citations
A patient with bipolar treatment-resistant depression who had not responded to medication, psychotherapy, or either repetitive transcranial magnetic stimulation (rTMS) or intravenous ketamine alone achieved complete and sustained remission when rTMS and ketamine were used together. The authors discuss how the two treatments may have complementary antidepressant mechanisms and call for further research on the combination's feasibility, tolerability, and efficacy.