Determination of psilocin and psilocybin using flow injection analysis with acidic potassium permanganate and tris(2,2′-bipyridyl)ruthenium(II) chemiluminescence detection respectively
Talanta February 17, 2005 Nicole Anastos, Neil W. Barnett, Simon W. Lewis et al. 32 citations
A new method using flow injection analysis with acidic potassium permanganate and tris(2,2'-bipyridyl)ruthenium(II) chemiluminescence can detect psilocin and psilocybin at very low concentrations—limits of detection are 9×10⁻¹⁰ M for psilocin and 3×10⁻¹⁰ M for psilocybin. The technique is simple, rapid, and sensitive. The paper also describes a concise three-step synthetic route for psilocin from readily available starting materials, with structures confirmed by spectroscopic data.