False-Positive LSD Testing in Urine Samples from Intensive Care Patients
Journal of Analytical Toxicology September 1, 1998 J. Röhrich, Siegfried Zörntlein, Johannes Lotz et al. 25 citations
A routine drug screening using the CEDIA DAU assay falsely identified lysergic acid diethylamide (LSD) in urine samples from 12 intensive care unit patients. None of these positive results were confirmed by high-performance liquid chromatography, but all samples contained the mucolytic drug ambroxol. Further investigation showed that ambroxol significantly cross-reacts with the CEDIA DAU LSD assay. Positive LSD results from this assay require careful evaluation, especially during cold season when mucolytic medications are more commonly used.