An ontogenic study of the behavioral effects of chronic intermittent exposure to ayahuasca in mice
Brazilian Journal of Medical and Biological Research January 1, 2017 Nelson Francisco Correa-Netto, M.y. Masukawa, F. Nishide et al. 20 citations
Exposure to ayahuasca during childhood increased risk assessment behavior, indicating anxiety, and during adolescence decreased time spent in the platform quadrant during a memory test, indicating spatial memory impairment, in C57BL/6 mice. The beverage did not affect locomotion or open arm exploration in the elevated plus maze, nor did it alter acquisition of spatial reference memory in the Morris water maze. These behavioral changes were not long-lasting, as they were absent in groups exposed from childhood to adulthood or adolescence to adulthood.