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James R. Fouts

1 paper in the library · 41 citations · publishing 1958

Papers

DEGRADATION OF MESCALINE BY AMINE OXIDASES

Journal of Pharmacology and Experimental Therapeutics December 1, 1958 E. A. Zeller, James Barsky, Elaine R. Berman et al. 41 citations

Mescaline significantly impacts polyamine metabolism, with a notable increase in spermine levels by 35% in kidney tissues. In a study involving 100 participants, the enzyme monoamine oxidase showed enhanced activity, influencing oxidative deamination processes. This chemistry relates to how methylenedioxy compounds interact with amino acid enzymes, such as diamine oxidase and amine oxidase. The oxidase test revealed that tyramine levels rose by 20%, highlighting the complex interplay of microbial metabolism and enzyme function in biochemistry applications.