The psychoactive effects of repeated ketamine infusions and their mechanistic role in the treatment of alcohol use disorder: Secondary analysis of a randomised controlled trial
Addiction February 16, 2026 Cassie Bloy, Ananya Sarma, Bethan Marsh et al. 1 citation
People with alcohol use disorder experience changes in consciousness from 0.8 mg/kg intravenous ketamine administration. Ketamine's effects remain broadly consistent across three repeated infusions. Reductions in alcohol consumption linked to ketamine do not appear to be caused by the acute psychoactive effects of the drug.