5-Meo-DALT-induced Cyclic Myoclonus (P3.013)
Neurology April 6, 2015 Thananan Thammongkolchai, Pichet Termsarasab, Ayham Alkhachroum et al. 43 citations
A 29-year-old man with a history of heroin and marijuana abuse developed intermittent myoclonus affecting his limbs, trunk, neck, and jaw in a cyclic pattern about every 10 minutes, along with unresponsiveness, after using the hallucinogen 5-MeO-DALT. His symptoms improved gradually over a week, and a dose of lorazepam temporarily stopped the myoclonus and partially restored consciousness. Standard urine toxicology did not detect the substance, and brain imaging and EEG were normal. This is the first reported case linking 5-MeO-DALT abuse to myoclonus, suggesting that clinicians should consider this drug in patients with unexplained cyclic myoclonus and negative toxicology screens.