Sustained Effects of Low-to-Moderate Doses of Psilocybin on Brain Connectivity
medRxiv Preprint Server April 17, 2026 Chiranth Bhagavan, Orwa Dandash, Olivia Carter et al. preprint
Psilocybin, a classic psychedelic, acutely alters brain functional connectivity, and these changes are linked to therapeutic doses and subjective effects. Some evidence indicates that such changes persist beyond the acute drug administration period. However, the effects of lower doses on sustained connectivity changes remain unclear.