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J. L. T. Birley

1 paper in the library · 33 citations · publishing 1977

Papers

Urinary dimethyltryptamine and psychiatric symptomatology and classification

Psychological Medicine February 1, 1977 R. Rodnight, R. M. Murray, M. C. H. Oon et al. 33 citations

Dimethyltryptamine (DMT) was detected in the urine of 47% of patients diagnosed with schizophrenia, 38% of those with other non-affective psychoses, 13% of those with affective psychoses, 19% of those with neurotic and personality disorders, and 5% of normal subjects. Operational definitions of psychosis did not identify any group more strongly associated with urinary DMT than a hospital diagnosis of schizophrenia. A discriminant function analysis of symptoms identified a group of 21 patients, of whom 71% excreted detectable DMT. A general relationship between psychotic symptoms and urinary DMT existed, but specifically schizophrenic symptoms were not major determinants of DMT excretion.