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Bernardo Bozza

University of Florence

3 papers in the library · 4 citations · publishing 2023-2024

Papers

Creative Minds: Altered Salience as a Bridge Between Creativity and Psychosis, a Case–Control Study

The Journal of Creative Behavior June 17, 2024 Andrea Patti, Giuseppe Pierpaolo Merola, Davide Benedetti et al. 2 citations

Artists report higher levels of aberrant salience—the tendency to attribute unusual significance to stimuli—than both healthy controls and patients with psychosis. In a study of 196 healthy controls, 50 artists from the Florence Academy of Fine Arts, and 84 outpatients diagnosed with psychosis, artists scored significantly higher on the Aberrant Salience Inventory. Group membership was the only factor influencing scores; age, gender, education, and antipsychotic treatment did not. The authors suggest that aberrant salience, rather than being solely a marker of pathology, may enhance creative faculties and unique perceptual experiences, and that education might help channel these mechanisms through art.

The role of psychotic‐like experiences in the association between aberrant salience and anxiety: A psychopathological proposal based on a case–control study

Early Intervention in Psychiatry December 8, 2023 Giuseppe Pierpaolo Merola, Andrea Patti, Davide Benedetti et al. 2 citations

Aberrant salience (AS) and psychotic-like experiences (PLEs) are linked, and anxiety is common in psychosis-prone individuals and patients. In a study of 163 healthy controls and 44 psychotic patients, AS correlated with more frequent positive PLEs and higher anxiety in both groups. However, the frequency of positive PLEs mediated the relationship between AS and anxiety only among controls, not patients. The authors suggest that in patients, a progressive loss of novelty and insight may impair emotional reactivity to PLEs and the ability to recognize bodily phenomena as anxiety, explaining the difference.

Introducing the ASI-NPI project: preliminary analysis of a study exploring the role of cannabis, salience alterations and youth in determining psychotic symptoms severity

Research Square November 20, 2023 Ottone Baccaredda Boy, Giuseppe Pierpaolo Merola, Andrea Patti et al.

Adolescents reported more severe psychotic symptoms on the Positive and Negative Syndrome Scale than adults, while no significant difference was found in cannabis exposure or Aberrant Salience Inventory scores. A hierarchical pattern emerged among adult subgroups, with psychotic patients scoring higher than other psychiatric and neurological patients. The findings suggest that aberrant salience, and to a lesser degree cannabis use, may contribute to psychotic symptom severity, particularly during more at-risk developmental phases. The role of cannabis in this relationship remains unclear.