Effects of naturalistic doses of cannabis edibles on cognition and association with blood THC.
Psychopharmacology March 1, 2026 Patricia Di Ciano, Sampson Zhao, Pamela Kaduri et al. 2 citations
Taking a low-dose cannabis edible (average 7.3 mg of THC) leads to measurable decreases in verbal learning and memory, specifically on two measures of a free recall task, 150 minutes after ingestion. No effects were found on visual attention or executive function as measured by the useful field of view and trail making tests. Subjective feelings of intoxication increased, but blood THC levels did not correlate with any cognitive performance changes. The results suggest that people who use relatively low doses of cannabis edibles may experience some cognitive decrements while feeling intoxicated.