Psilocybin reduces symptoms in treatment resistant depression, trial results show
British medical journal November 2, 2022 G. Iacobucci 5 citations
A single 25 mg dose of psilocybin, given with psychological support, reduced depression scores more than a 1 mg control dose over 12 weeks in 233 patients with treatment-resistant depression. The 10 mg dose showed intermediate effects. Participants received the drug in calming, non-clinical rooms with a therapist present during the eight-hour psychedelic session and then returned home. The results suggest that psilocybin can be a useful treatment for this difficult-to-treat condition.