TUSI Valve: Echocardiographic and Pathologic Correlates of a Novel Drug-Induced Valvular Disease-a Case Series.
CASE April 1, 2026 Juan Felipe Vasquez-Rodriguez, Gustavo Lemus-Barrios, Diego Rangel-Rivera et al.
Use of TUSI ("pink cocaine") may cause serotonin-mediated drug-induced valvular heart disease. Echocardiography shows reproducible thickening and restricted motion of the atrioventricular valves. Histological examination reveals myxoid degeneration without inflammatory infiltrate. Young patients with unexplained valve regurgitation should be screened for drug use. Synthetic drug use poses emerging cardiovascular risks that require attention.