Exploring novel therapeutic strategies: Could psychedelic perspectives offer promising solutions for Alzheimer's disease comorbidities?
Dialogues Clin Neurosci March 19, 2025 Michael Davidson, Gabriela-Dumitrita Stanciu, Jonathan Rabinowitz et al. 2 citations
This theoretical paper explores whether psychedelic-assisted therapy could address comorbidities often accompanying Alzheimer's disease, such as depression, anxiety, and social withdrawal. The authors argue that psychedelics may promote neuroplasticity, reduce inflammation, and facilitate psychological breakthroughs that improve quality of life. They suggest that combining psychedelic compounds with psychotherapy might offer a novel approach to managing behavioral and psychological symptoms of dementia. The paper calls for further research into safety, dosing, and ethical considerations for this vulnerable population, noting that current evidence is preliminary and based largely on extrapolation from studies in other conditions.