Refractory CRPS pain treated with psilocybin: A case report
David S Jevotovsky, Harman Chopra, Court Wing, Carlton J Spotswood, Joel Castellanos
Clinical Case Reports September 1, 2024 DOI: 10.1002/ccr3.9421 via OpenAlex
Summary
AI-generated from the abstractA single patient with complex regional pain syndrome (CRPS) that did not respond to standard treatments experienced substantial pain relief and improved function after taking psilocybin. This case suggests psilocybin may be a promising therapy for refractory CRPS, but more research is needed to determine its effectiveness and the best dosage for chronic pain.
Study at a glance
| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A patient with refractory complex regional pain syndrome |
| Intervention | Psilocybin |
| Topics | Psilocybin Psychedelic-assisted therapy |
| Keywords | Medical research Chronic pain Psychedelics |
| Citations | 9 |
| Key finding | Psilocybin provided significant pain relief and functional improvement in a patient with treatment-resistant CRPS. |
Abstract
Key Clinical Message Psilocybin shows promise as a treatment for CRPS, offering significant pain relief and functional improvement in a patient with refractory symptoms. This case highlights the need for further research into psilocybin's efficacy and optimal dosing for chronic pain management.