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Effect of online mindfulness intervention on anxiety, depression, and stress in patients with chronic diseases.

Ying-Ju Chen, Chiu-Hsiang Lee, Chia-Jung Hsieh, Pei-Hung Liao, Yu-Da Chen, Kuei-Ru Chou, Shu-Liu Guo, Li-Fang Chang, Tso-Ying Lee

Explore (New York, N.Y.) July 8, 2025 DOI: 10.1016/j.explore.2025.103214 via PubMed

Summary

AI-generated from the abstract

An online mindfulness platform reduced anxiety, depression, and stress in adults with chronic diseases. In a randomized trial, 97 patients were assigned to either an online mindfulness program or a control group. Anxiety scores dropped significantly at 4 weeks and 8 weeks after the intervention. Depression and stress levels were significantly lower at 8 weeks, but not at 4 weeks. The findings suggest that online mindfulness can be an effective non-pharmacological option for managing mental health symptoms in this population.

Study at a glance

Characteristics Randomized controlled trial Qualitative Peer reviewed
Sample size 97
Population Patients with chronic diseases
Intervention Online mindfulness platform
Duration 8-week intervention, assessments at baseline, 4 weeks, and 8 weeks
Topics Anxiety Depression
Keywords Adults Chronic disease Online mindfulness platform
Citations 1
Key finding Online mindfulness intervention significantly reduced anxiety at 4 and 8 weeks, and reduced depression and stress at 8 weeks, in adults with chronic diseases.

Abstract

Online mindfulness may be an effective non-pharmacological mental health intervention. To evaluate the effectiveness of an online mindfulness platform in ameliorating anxiety, depression, and stress in patients with chronic diseases. In this randomized controlled study, 97 patients were enrolled and randomly assigned to either the online intervention group (N = 47) or the control group (N = 50). Anxiety, depression, and stress levels were assessed at baseline, 4 weeks, and 8 weeks after the intervention. The baseline scores of anxiety, depression, and stress between the control and experiment groups were comparable. Online mindfulness intervention significantly reduced anxiety scores at Week 4 and Week 8 (both P < 0.001). In addition, online mindfulness intervention significantly lowered both depression scores and stress levels at Week 8 (both P ≤ 0.002), but not at Week 4. Online mindfulness interventions effectively alleviate anxiety, depression, and stress in patients with chronic diseases. Future qualitative research is recommended to further explore the mechanisms of change at the psychological level.

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