Psychedelic Drugs or Hallucinogens: Exploring Their Medicinal Potential.
Priyanshu Raj, Shyambabu Rauniyar, Bhagyesh Sapkale
Cureus November 1, 2023 DOI: 10.7759/cureus.48719 via PubMed
Summary
AI-generated from the abstractSerotonergic hallucinogens, or psychedelics, such as LSD and psilocybin, profoundly alter perception, mood, and cognition by acting on serotonin receptors. Contemporary research recognizes their therapeutic value, showing promise for treating depression, PTSD, and anxiety through effects on neuroplasticity. Compared to alcohol, LSD and psilocybin are relatively safer. The modern revival of scientific interest calls for viewing these substances as therapeutic tools rather than recreational ones, necessitating rigorous investigation and societal discourse to dispel myths and harness their potential for treating mental illness.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Keywords | Hallucinogens uses Psychedelic drug research Psychedelic drugs Psychedelic medicines Mental health treatment |
| Citations | 8 |
| Key finding | Serotonergic hallucinogens like LSD and psilocybin show therapeutic potential for neuropsychiatric disorders such as depression, PTSD, and anxiety, and are relatively safer than alcohol. |
Abstract
Serotonergic hallucinogens also referred to as psychedelics, are psychoactive substances that profoundly alter perception, mood, and cognitive processes. These substances, historically intertwined with religious and cultural rituals, offer profound effects that extend beyond mere hallucinations to profoundly altered states of consciousness. Notable compounds like Lysergic acid diethylamide (LSD) and psilocybin, potent in their action on serotonin receptors, play pivotal roles in influencing brain functions. Despite societal misconceptions that have overshadowed their potential, contemporary research increasingly recognizes their therapeutic value. These substances have shown promise in treating neuropsychiatric disorders such as depression, post-traumatic stress disorder (PTSD), and anxiety, leveraging their influence on neuroplasticity. Furthermore, they exhibit therapeutic potential across various conditions, challenging conventional treatment methodologies. Compared to substances like alcohol, traditional psychedelics like LSD and psilocybin emerge as relatively safer substances. The modern revival of scientific interest in psychedelics necessitates a renewed perspective, viewing them not just as recreational entities but as potent therapeutic tools. Harnessing their actual value mandates rigorous scientific investigations and a receptive societal discourse. A re-evaluation of their classification following international criteria is necessary in light of this increasing understanding. Hallucinogens or psychedelic drugs, if used correctly, can potentially be potential treatments for mental illness, signalling a paradigm shift from traditional techniques. To dispel myths and use their therapeutic advantages, embracing this potential necessitates thorough scientific investigation together with an open societal discourse.