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Assessing potential of psilocybin for depressive disorders

Zofia Kozak, Matthew W Johnson, Scott T Aaronson

Expert Opinion on Investigational Drugs October 3, 2023 DOI: 10.1080/13543784.2023.2273493 via OpenAlex

Summary

AI-generated from the abstract

Patients with treatment-resistant depression may be the most suitable candidates for psilocybin treatment when weighing known risks and benefits against existing standards of care. Much remains unknown about the risks of psilocybin treatment.

Study at a glance

Characteristics Review Peer reviewed
Population Patients with depression, specifically those with treatment-resistant depression
Topics Depression Psychedelic-assisted therapy
Keywords Psilocybin, psychedelics Magic mushroom therapy Treatment-resistant depression trd
Citations 10
Key finding Patients with treatment-resistant depression may be the most suitable candidates for psilocybin treatment at this time.

Abstract

There is still much unknown regarding the risks of psilocybin treatment. When weighing the known risks and benefits of psilocybin treatment against those found in existing standards of care, among patients with depression, patients with treatment-resistant depression (TRD) may be the most suitable candidates for psilocybin treatment at this time.

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