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Proposed Consensus Statement on Defining Psychedelic Drugs.

David E. Nichols, Charles D. Nichols, Peter S. Hendricks

Psychedelic Med (New Rochelle) March 13, 2023 DOI: 10.1089/psymed.2022.0008 via PubMed Central

Summary

AI-generated from the abstract

A proposed consensus statement defines psychedelic drugs as substances that reliably produce profound alterations in consciousness, perception, and mood through agonist activity at the serotonin 2A receptor. The definition emphasizes pharmacological mechanism over subjective effects, distinguishing psychedelics from other psychoactive compounds. The authors argue that a standardized definition is essential for advancing medical research, drug development, and clinical applications by providing a clear framework for classification and nomenclature. This consensus aims to reduce ambiguity in scientific and therapeutic contexts, supporting more precise communication and regulatory clarity in psychedelic research.

Study at a glance

Characteristics Theoretical or philosophical paper Peer reviewed
Keywords Psychedelic drugs Psychedelics Hallucinogens Entheogens Psychoactive compounds
Citations 39
Key finding A consensus definition of psychedelic drugs based on serotonin 2A receptor agonism is proposed to standardize terminology and support medical research.

Abstract

Proposed Consensus Statement on Defining Psychedelic Drugs.

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