Development and application of a highly sensitive LC-MS/MS method for simultaneous quantification of N,N-dimethyltryptamine and two of its metabolites in human plasma.
Emma Eckernäs, Adam Bendrioua, Chiara Cancellerini, Christopher Timmermann, Robin Carhart-Harris, Kurt-Jürgen Hoffmann, Michael Ashton
J Pharm Biomed Anal February 3, 2022 DOI: 10.1016/j.jpba.2022.114642 via PubMed
Summary
AI-generated from the abstractA highly sensitive LC-MS/MS method was developed and applied to simultaneously quantify N,N-dimethyltryptamine (DMT) and two of its metabolites in human plasma. This new method accurately and precisely measures DMT and its breakdown products, providing a robust tool for studying how DMT behaves in the body, its metabolism, and its effects.
Study at a glance
| Characteristics | Method development and validation Peer reviewed |
|---|---|
| Keywords | DMT Research DMT Natural compounds Substances DMT'S Effects DMT'S Metabolism |
| Citations | 18 |
| Key finding | A highly sensitive LC-MS/MS method was developed and applied for simultaneous quantification of DMT and two of its metabolites in human plasma. |
Abstract
Development and application of a highly sensitive LC-MS/MS method for simultaneous quantification of N,N-dimethyltryptamine and two of its metabolites in human plasma.