First study of safety and tolerability of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy in patients with alcohol use disorder: preliminary data on the first four participants.
Ben Sessa, Chloe Sakal, Steve O’Brien, David Nutt
BMJ Case Rep July 15, 2019 DOI: 10.1136/bcr-2019-230109 via PubMed Central
Summary
AI-generated from the abstractIn a preliminary safety study of MDMA-assisted psychotherapy for alcohol use disorder, the first four participants tolerated the treatment without serious adverse events. The combination of MDMA with psychotherapy was feasible and acceptable, though the small number of participants limits conclusions about efficacy. These early results suggest that further research into this approach for alcohol dependence is warranted.
Study at a glance
| Characteristics | Safety study Peer reviewed |
|---|---|
| Sample size | 4 |
| Population | Patients with alcohol use disorder |
| Topics | Addiction Psychedelic-assisted therapy |
| Keywords | MDMA Therapy MDMA-Assisted Psychotherapy Ecstasy treatment |
| Citations | 55 |
| Key finding | MDMA-assisted psychotherapy was safe and tolerable in the first four participants with alcohol use disorder. |
Abstract
First study of safety and tolerability of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy in patients with alcohol use disorder: preliminary data on the first four participants.