Psychedelic and MDMA-Related Adverse Effects-A Call for Action.

Psychedelic and MDMA therapies carry potential risks that must be better understood to ensure safe and ethical practice. This viewpoint identifies four key research goals: characterizing adverse effects, understanding how context influences outcomes, developing risk mitigation strategies, and establishing guidelines for safe administration. The authors argue that rigorous investigation of these risks is essential before widespread clinical adoption, emphasizing that safety concerns should be addressed proactively rather than reactively.

Study at a glance

Abstract

This Viewpoint discusses the need to better understand potential risks associated with psychedelic and 3,4-methylenedioxymethamphetamine (MDMA) use to ensure safe and ethical practice and identifies 4 key research goals.