Anti-Inflammatory Effects of Four Psilocybin-Containing Magic Mushroom Water Extracts in vitro on 15-Lipoxygenase Activity and on Lipopolysaccharide-Induced Cyclooxygenase-2 and Inflammatory Cytokines in Human U937 Macrophage Cells
Sanah Malomile Nkadimeng, Christiaan Ml Steinmann, J.n. Eloff
Journal of Inflammation Research August 1, 2021 DOI: 10.2147/jir.s317182 via OpenAlex
Summary
AI-generated from the abstractHot-water extracts from four types of psilocybin-containing magic mushrooms may reduce inflammation by decreasing levels of pro-inflammatory signaling molecules. The findings suggest these extracts have potential anti-inflammatory properties through the suppression of inflammatory mediators.
Study at a glance
| Characteristics | Laboratory study Peer reviewed |
|---|---|
| Population | Psilocybin-containing magic mushrooms |
| Keywords | Lipopolysaccharide U937 cell Cyclooxygenase Inflammation Pharmacology |
| Citations | 77 |
| Key finding | Hot-water extracts of four psilocybin-containing magic mushrooms down-regulate pro-inflammatory mediators, indicating potential anti-inflammatory effects. |
Abstract
The study suggested that the hot-water extracts of the four psilocybin-containing magic mushrooms have potential anti-inflammatory effects executed by down-regulating pro-inflammatory mediators.