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Psilocybin und Psilocin, zwei psychotrope Wirkstoffe aus mexikanischen Rauschpilzen

A. Hofmann, Richard R. Heim, A. Brack, H. Kobel, A. Frey, H. Ott, Th. Petrzilka, F. Troxler

Helvetica Chimica Acta January 1, 1959 DOI: 10.1002/hlca.19590420518 via OpenAlex

Summary

AI-generated from the abstract

The psychotropically active compounds of the Mexican hallucinogenic fungus Psilocybe mexicana were isolated and crystallized. Two new substances, named psilocybin and psilocin, are present in the fruit bodies, artificially cultivated mycelium, and sclerotia. The dried mushroom contains 0.2 to 0.4 percent psilocybin; psilocin is present at most in trace amounts only.

Study at a glance

Characteristics Chemical isolation study Peer reviewed
Population Psilocybe mexicana fungus
Topics Psilocybin
Keywords Hallucinogen Mycelium Stereochemistry
Citations 225
Key finding Psilocybin and psilocin were isolated as the psychotropic principles of Psilocybe mexicana, with psilocybin comprising 0.2 to 0.4 percent of the dried mushroom and psilocin present only in trace amounts.

Abstract

Abstract The psychotropically active principles of the Mexican hallucinogenic fungus Psilocybe maxicana H EIM have been isolated and obtained in crystalline form. The two new substances, which have been called psilocybin and psilocin , are present in the fruit bodies, the artificially cultivated mycelium and in the sclerotia. The dried mushroom contains 0.2 to 0.4 per cent psilocybin. Psilocin is present, at the most, in trace amounts only.

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