The therapeutic potential of psilocybin: a systematic review
Jan Van Amsterdam, Wim van den Brink
Expert Opinion on Drug Safety February 26, 2022 DOI: 10.1080/14740338.2022.2047929 via OpenAlex
Summary
AI-generated from the abstractPsilocybin, when combined with psychotherapy or psychotherapeutic support, shows promise as a treatment for various mental disorders, including treatment-resistant conditions. However, larger double-blind randomized controlled trials with objective long-term outcomes are needed to confirm these findings before standard clinical use can be considered.
Study at a glance
| Characteristics | Review Double-blind Peer reviewed |
|---|---|
| Interventions | Psilocybin Psychotherapy |
| Topics | Psilocybin |
| Keywords | Medicine Adverse effect Hallucinogen Placebo |
| Citations | 74 |
| Key finding | Psilocybin combined with psychotherapy shows promise for treating mental disorders, but larger double-blind RCTs with long-term outcomes are needed before standard clinical use. |
Abstract
Psilocybin - mostly combined with psychotherapy or psychotherapeutic support - shows a promise as a treatment for various (treatment-resistant) mental disorders. Larger double-blind RCTs with objective (long-term) outcomes are needed to confirm these findings before standard clinical use of psilocybin can be considered.