Poisoning by hallucinogenic mushroom Hikageshibiretake (Psilocybe argentipes K. Yokoyama) indigenous to Japan.

Five cases of poisoning by the indigenous mushroom Hikageshibiretake (Psilocybe argentipes) are described. Since this mushroom contains psilocybin, clinical features generally resembled those of pure psilocybin. One case involved an acute toxic stuporous state with complete amnesia during the culminating period, one case involved a psychedelic state with dreamy consciousness, and three cases involved psychotic adverse reactions with vivid visual hallucinations while conscious. These experiences were accompanied by anxiety and panic reactions. Although the toxic effects were usually short-lived, the report emphasizes that horrible emotional reactions and harmful behavioral problems can occur, which is important for patient management.

Study at a glance

Abstract

Five cases of poisoning by indigenous mushroom Hikageshibiretake (Psilocybe argentipes) are reported. As this mushroom contains psilocybin, in general, clinical features were similar to those seen by pure psilocybin. Acute toxic stuporous state with complete amnesia in the culminating period occurred in one case, psychedelic state with dreamy consciousness in one case and psychotic adverse reactions with vivid visual hallucinations with consciousness in three cases. There were accompanied with anxiety and panic reactions to subjective experiences. Though these toxic effects were usually short-lived, for management of such patients it is important to recognize that horrible emotional reactions and other harmful behavioral problems can also occur.