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Psilocybin‐assisted therapy reduces heavy drinking in patients with AUD

The Brown University Psychopharmacology Update November 3, 2022 DOI: 10.1002/pu.30946 via OpenAlex

Summary

AI-generated from the abstract

Two sessions of psilocybin-assisted psychotherapy reduced heavy-drinking days and other alcohol-related problems more than placebo plus psychotherapy in a randomized trial of patients with alcohol use disorder. No serious adverse events or psychotic disturbances occurred with psilocybin. Results appeared in JAMA Psychiatry.

Study at a glance

Characteristics Randomized controlled trial Peer reviewed
Population Patients with alcohol use disorder
Topics Addiction Psilocybin
Keywords Adverse effect Placebo Hallucinogen
Key finding Two sessions of psilocybin-assisted psychotherapy reduced heavy-drinking days and other alcohol-related problems compared to placebo plus psychotherapy.

Abstract

Two sessions of psilocybin‐assisted psychotherapy resulted in reduced heavy‐drinking days and other alcohol‐related problems relative to placebo plus psychotherapy in a randomized trial involving patients with alcohol use disorder (AUD). There were no serious adverse events associated with psilocybin administration, and no signs of psychotic disturbances. Study results were published online Aug. 24, 2022, in JAMA Psychiatry .

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