Use of Psilocybin in the Treatment of Mental Disorders: Systematic Review of Clinal Trials

A systematic review of clinical trials assessed the neurobiology, efficacy, safety, and feasibility of psilocybin for treating depression, anxiety, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), smoking, and alcoholism. The review suggests psilocybin shows promise for several mental disorders, with evidence indicating potential benefits, particularly for depression and anxiety. The findings highlight the need for further research to confirm efficacy and safety across these conditions.

Study at a glance

Abstract

Title: Use of psilocybin in the treatment of mental disorders: systematic review of clinical trials. Objective: To evaluate the high-impact evidence on the neurobiology, efficacy, safety, and feasibility of using psilocybin in the treatment of mental disorders such as depression, anxiety, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), smoking, and alcoholism