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Study finds encouraging results in psilocybin treatment for TRD patients

Valerie A. Canady

Mental Health Weekly January 10, 2025 DOI: 10.1002/mhw.34292 via OpenAlex

Summary

AI-generated from the abstract

In an open-label study of patients with severe treatment-resistant depression, synthetic psilocybin produced significant decreases in depressive symptoms. The treatment also showed significant safety and efficacy for this population.

Study at a glance

Characteristics Open-label study Peer reviewed
Population Patients with severe treatment resistant depression
Intervention Synthetic psilocybin
Topics Psilocybin
Keywords Psychology Medicine Hallucinogen
Key finding Synthetic psilocybin significantly reduced depressive symptoms and demonstrated safety and efficacy in patients with severe treatment-resistant depression.

Abstract

Results of new psychedelic research aimed at patients with severe treatment resistant depression (TRD) found significant decreases in their depressive symptoms. Researchers of the open‐label study also found significant safety and efficacy of synthetic psilocybin in TRD patients.

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