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Psilocybin Experiential Therapist Training: Insights from a World-First Study

Georgia Ioakimidis-Macdougall, John Gardner, Paul Liknaitzky

medRxiv November 17, 2025 preprint DOI: 10.1101/2025.11.15.25340324 via OpenAlex

Summary

AI-generated from the abstract

A single 25 mg dose of psilocybin, given with psychological support in a clinical setting, helped 14 mental health professionals develop a greater embodied understanding of therapeutic principles and processes. Participants reported increases in empathy, attunement, and emotion regulation—qualities that underpin therapeutic alliance and promote trust and safety. While no harms were reported, participants noted two potential risks: the experience could feel destabilizing, and therapists might project their own experience onto clients, narrowing interpretative range. Participants indicated that such training is necessary but not sufficient for high-quality psychedelic-assisted therapy. Findings support including an optional psychedelic experiential component for clinicians with prior training and reflective capacity.

Study at a glance

Characteristics Qualitative study with quantitative measures and semi-structured interviews
Sample size 14
Population Mental healthcare professionals training to provide psilocybin-assisted therapy
Intervention Psilocybin
Dose 25 mg
Topics Anxiety Psilocybin
Keywords Experiential learning Context archaeology Mental health Reflective practice
Key finding A single 25 mg dose of psilocybin in a clinical context helped mental health professionals develop embodied understanding of therapeutic principles and increased therapeutic qualities such as empathy, attunement, and emotion regulation.

Abstract

Abstract First-hand experience with psychedelics may help clinicians develop skills and knowledge needed to work with the profound changes to conscious awareness occasioned by psychedelics. However, the topic remains contentious and underexplored. In this world-first study, we investigated the utility of psilocybin experiential therapist training in a sample of 14 mental healthcare professionals training to provide psilocybin-assisted therapy. Participants received one 25 mg dose of psilocybin in a clinical research context alongside psychological support before, during, and after dosing. Quantitative measures and semi-structured interviews were then undertaken by participants to explore their experiences and reflections. Through the intervention, participants reported developing a greater and embodied understanding of key therapeutic principles and processes. Moreover, they reported increases in therapeutic qualities (e.g., empathy, attunement, emotion regulation) that underpin therapeutic alliance and promote trust and safety. While participants did not report experiencing harms from participation, they speculated about two potential risks of psychedelic experiential therapist training: first, that it could elicit challenging material that feels destabilising for a period; and second, that therapists could project their experience onto clients in a manner that narrows interpretative range and reduces attunement. Recommendations were made for psychedelic experiential therapist training design and implementation, including strategies to mitigate such risks. Participants indicated that psychedelic experiential therapist training is necessary but not sufficient for providing the highest quality of care in psychedelic-assisted therapy. Findings support the inclusion of an optional psychedelic experiential component within psychedelic therapist training programs for clinicians with prior psychotherapeutic training and well-developed reflective capacity.

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