Recommendations and Consensus Statements on Psilocybin-Assisted Psychotherapy (PAP) for Depression: A Rapid Review and Thematic Analysis
Aimee Freeburn, Alene Sze Jing Yong, Simon Bell
Open Science Framework January 1, 2025 DOI: 10.17605/osf.io/gzvb3 via OpenAlex
Summary
AI-generated from the abstractClinical guidelines and position statements from multiple countries recommend medical psilocybin-assisted psychotherapy for adults with depression, but they vary in their specific conditions and safeguards. The review of international documents shows consensus that PAP should be administered in controlled clinical settings with trained therapists, though recommendations differ on patient selection criteria, dosing protocols, and integration procedures. Most guidelines emphasize the need for further research to establish long-term safety and efficacy.
Study at a glance
| Characteristics | Systematic review Peer reviewed |
|---|---|
| Population | Adults living with depression |
| Intervention | Psilocybin-assisted psychotherapy |
| Keywords | Thematic analysis Psychology Psychotherapist Medline Position paper |
| Key finding | International clinical guidelines and position statements recommend psilocybin-assisted psychotherapy for depression but differ in specific implementation recommendations. |
Abstract
This rapid review aims to synthesise recommendations and statements from international clinical guidelines, consensus statements, and position statements regarding the medical use of psilocybin-assisted psychotherapy (PAP) in adults living with depression.