Monoamine Transporter and Receptor Interaction Profiles in Vitro Predict Reported Human Doses of Novel Psychoactive Stimulants and Psychedelics
Dino Luethi, Matthias E Liechti
The International Journal of Neuropsychopharmacology May 24, 2018 DOI: 10.1093/ijnp/pyy047 via OpenAlex
Summary
AI-generated from the abstractRapidly measuring the in vitro pharmacological activity of new psychoactive substances can help predict their psychoactive doses and effects in humans, aiding in the appropriate legal scheduling of these substances.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Serotonin |
| Keywords | Pharmacology Monoamine neurotransmitter Dopamine transporter Serotonin transporter Potency |
| Key finding | Rapid assessment of in vitro pharmacological profiles of new psychoactive substances can help predict psychoactive doses and effects in humans and facilitate appropriate scheduling. |
Abstract
The rapid assessment of in vitro pharmacological profiles of new psychoactive substances can help to predict psychoactive doses and effects in humans and facilitate the appropriate scheduling of new psychoactive substances.