Psychedelic pathways: Exploring reinforcement learning under psychedelic influence
Federico Cavanna, Enzo Tagliazucchi
Open Science Framework January 1, 2025 DOI: 10.17605/osf.io/52hxf via OpenAlex
Summary
AI-generated from the abstractPsilocybin acutely alters probabilistic reinforcement learning in healthy adults. In a double-blind, randomized, within-subject, placebo-controlled study, behavioral data and event-related potentials from EEG recordings will reveal how the psychedelic modulates neural mechanisms of reward processing and decision-making.
Study at a glance
| Characteristics | Randomized controlled trial Placebo-controlled Double-blind Peer reviewed |
|---|---|
| Population | Healthy adults |
| Intervention | Psilocybin |
| Topics | Psilocybin |
| Keywords | Cognitive psychology Reinforcement learning Neural activity Electroencephalography |
| Key finding | Psilocybin modulates neural mechanisms of reward processing and decision-making during probabilistic reinforcement learning. |
Abstract
This project investigates the acute effects of psilocybin on probabilistic reinforcement learning in healthy adults. Using a double blind, randomized, within-subject, placebo-controlled design, we will analyze behavioral data and Event-Related Potentials (ERPs) from EEG recordings to understand how psychedelics modulate neural mechanisms of reward processing and decision-making.