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Therapeutic benefit versus epistemic risk: Need for empirical research in psychedelic epistemology.

Lucas F Borkel, Jaime Rojas-Hernández, Domingo J Quintana-Hernández, Luis Alberto Henríquez-Hernández

Journal of psychiatric research August 1, 2025 DOI: 10.1016/j.jpsychires.2025.05.039 via PubMed

Summary

AI-generated from the abstract

Psychedelic therapy, while physiologically and psychologically safe, can alter users' beliefs, including inducing paranormal beliefs. This paper introduces the concept of epistemic criteria—the principles people use to validate and justify their beliefs—and hypothesizes that psychedelics may change beliefs by modifying these criteria. The authors argue that this potential, under-researched risk highlights ethical and epistemic challenges, vindicating the importance of epistemology in clinical and psychotherapeutic settings. Further research is needed to determine the extent of this risk.

Study at a glance

Characteristics Theoretical or philosophical paper Peer reviewed
Topics Psychedelic-assisted therapy
Keywords Belief systems Mental health treatment Epistemology Consciousness alteration
Citations 4
Key finding Psychedelics may alter beliefs by modifying individuals' epistemic criteria, posing an under-researched ethical and epistemic risk in therapy.

Abstract

This paper highlights the ethical and epistemic challenges posed by psychedelic therapy and vindicates the importance of epistemology in the clinical and psychotherapeutic setting. Despite their relative physiological and psychological safety, these substances can induce changes in the beliefs of those who use them, such as paranormal beliefs. To explain the changes in beliefs, we introduced the concept of epistemic criteria (i.e., the principles individuals use to validate and justify their beliefs) and hypothesized that psychedelics may alter beliefs by modifying epistemic criteria. Further research should be conducted to determine this potential and under-researched risk of psychedelic therapy.

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